Geschmack ist vorhersagbar: Mit FlavorMiner. FlavorMiner heißt das Tool, das IPB-Chemiker und Partner aus Kolumbien jüngst entwickelt haben. Das Programm kann, basierend auf maschinellem Lernen (KI), anhand der…
Seit Februar 2021 bietet Wolfgang Brandt, ehemaliger Leiter der Arbeitsgruppe Computerchemie am IPB, sein Citizen Science-Projekt zur Pilzbestimmung an. Dafür hat er in regelmäßigen Abständen öffentliche Vorträge zur Vielfalt…
Reisberg, M.; Arnold, N.; Porzel, A.; Neubert, R. H. H.; Dräger, B.;Production of Rare Phyto-Ceramides from Abundant Food Plant ResiduesJ. Agr. Food Chem.651507-1517(2017)DOI: 10.1021/acs.jafc.6b04275
Ceramides (Cers) are major components of the outermost layer of the skin, the stratum corneum, and play a crucial role in permeability barrier functions. Alterations in Cer composition causing skin diseases are compensated with semisynthetic skin-identical Cers. Plants constitute new resources for Cer production as they contain glucosylceramides (GluCers) as major components. GluCers were purified from industrial waste plant materials, apple pomace (Malus domestica), wheat germs (Triticum sp.), and coffee grounds (Coffea sp.), with GluCer contents of 28.9 mg, 33.7 mg, and 4.4 mg per 100 g of plant material. Forty-five species of GluCers (1–45) were identified with different sphingoid bases, saturated or monounsaturated α-hydroxy fatty acids (C15–28), and β-glucose as polar headgroup. Three main GluCers were hydrolyzed by a recombinant human glucocerebrosidase to produce phyto-Cers (46–48). These studies showed that rare and expensive phyto-Cers can be obtained from industrial food plant residues.
Publikation
Anh, N. T. H.; Thuy, T. T.; Sung, T. V.; Dan, T. K.; Chinh, N. B.; Quang, N.; Franke, K.; Arnold, N.; Wessjohann, L.;Phytochemical study on the plants of the antidrug medication heantos 4: Part 3. Homoisoflavonoid, flavonoid and phenolic compoundsVietnam J. Chem.51358-362(2013)
Anh, N. T. H.; Thuy, T. T.; Sung, T. V.; Dan, T. K.; Chinh, N. B.; Quang, N.; Franke, K.; Arnold, N.; Wessjohann, L.;Phytochemical study on the plants of the antidrug medication heantos 4: Part 2. Terpenoid- and steroid compoundsVietnam J. Chem.51190-194(2013)
Thuy, T. T.; Anh, N. T. H.; Sung, T. V.; Dan, T. K.; Chinh, N. B.; Quang, N.; Franke, K.; Arnold, N.; Wessjohann, L.;Phytochemical study on the plants of the antidrug medication heantos 4: Part 4. Phthalides, fatty acids, oligosaccharide esters and miscellaneous compoundsVietnam J. Chem.51546-550(2013)