Dem IPB wird erneut ein beispielhaftes Handeln im Sinne einer chancengleichheitsorientierten Personal- und Organisationspolitik bescheinigt. Das Institut erhält zum 6. Mal in Folge das TOTAL E-QUALITY…
Die Plant Science Student Conference (PSSC) wird seit 20 Jahren im jährlichen Wechsel von Studierenden der beiden Leibniz-Institute IPK und IPB organisiert. Im Interview erläutern Christina Wäsch…
Blatt-Janmaat, K.; Neumann, S.; Schmidt, F.; Ziegler, J.; Peters, K.; Qu, Y.;Impact of in vitro hormone treatments on the bibenzyl production of Radula complanataBotany101232 - 242(2022)DOI: 10.1139/cjb-2022-0048
Bibenzyls are a specialized metabolite class found throughout the plant kingdom. One of the most prolific producers of bibenzyls are liverworts, specifically plants of the Radula genera. These plants possess an incredible diversity of bibenzyls, prenylated bibenzyls, and a few (bis)bibenzyls, several of which have medicinal properties, including perrottetinene, an analog of tetrahydrocannabinol from cannabis. To provide insight into the bibenzyls’ biosynthesis in planta, exogenous phytohormones were applied to in vitro grown Radula complanata and bibenzyl metabolite production was monitored with targeted and untargeted metabolomics. The targeted metabolomic analysis of six prenylated bibenzyls revealed that production of these metabolites was largely reduced when plants were treated with abscisic acid (AA), salicylic acid (SA), 1-naphthaleneacetic acid (NAA), or 6-benzylaminopurine (BAP). The reduction of these metabolites in the BAP and NAA treatment suggests that prenylated bibenzyl production is negatively correlated with vegetative plant growth. The reduction of bibenzyls at low AA and SA concentrations and mild increase at higher AA and SA concentrations suggest that their production is regulated by these stress hormones. In addition, six other bibenzyl metabolites were tentatively identified from the untargeted analysis. These results provide insight into the influence of phytohormones on the bioactive bibenzyl content of R. complanata.
Publikation
Greff, A.; Porzel, A.; Schmidt, J.; Palfner, G.; Arnold, N.;Pigment pattern of the Chilean mushroom Dermocybe nahuelbutensis Garrido & E. HorakRec. Nat. Prod.11547-551(2017)DOI: 10.25135/rnp.69.17.01.027
Fruiting bodies of the Chilean mushroom Dermocybe nahuelbutenis Garrido & E. Horak (syn.: Cortinariusnahuelbutensis (Garrido & E. Horak) E. Valenz. & G. Moreno) were chemically investigated for the first time andafforded the new dimeric anthraqinone 7,7'-emodinphyscion (1) beside the know anthraquinones dermolutein (2),endocrocin (3), skyrin (4) and the dimeric pre-anthraquinone derivative flavomannin C (5). The chemotaxonomicsignificance of the pigments is discussed.
Publikation
Alresly, Z.; Lindequist, U.; Lalk, M.; Porzel, A.; Arnold, N.; Wessjohann, L. A.;Bioactive Triterpenes from the Fungus Piptoporus betulinusRec. Nat. Prod.10103-108(2016)
Phytochemical investigation of the ethyl acetate extract of the fruiting bodies from the basidiomycete Piptoporus betulinus led to the isolation of a new bioactive lanostane triterpene identified as 3 b -acetoxy-16-hydroxy-24-oxo-5α-lanosta-8- ene-21-oic acid (1). In addition, ten known triterpenes, polyporenic acid A (5), polyporenic acid C (4), three derivatives of polyporenic acid A (8, 10, 11), betulinic acid (3), betulin (2), ergosterol peroxide (6), 9,11-dehydroergosterol peroxide (7), and fomefficinic acid (9), were also isolated from the fungus. All isolated compounds were tested for antimicrobial activity against some Gram-positive and Gram-negative bacteria as well as against a fungal strain. The new triterpene and some of the other compounds showed antimicrobial activity against Gram-positive bacteria.
Publikation
Ali, N. A. A.; Wurster, M.; Arnold, N.; Lindequist, U.; Wessjohann, L.;Essential Oil Composition from Oleogum Resin of Soqotraen Commiphora kuaRec. Nat. Prod.270-75(2008)
The major constituents of the essential oil obtained by hydrodistillation from the oleogum resin of Commiphora kua Vollesen were identified by GC-MS. Sixteen constituents were detected from the essential oil, which constituted about (90.5%) of the total amount. Major constituents of the oil were α- cadinol (33.0%), g -cadinene (22.5%), d -cadinene (17.0%), isocaryophyllene (3.7%), allo-aromadendrene (2.8%), α-muurolene (2.7%), and α-humulene (2.4%). The Oil of Commiphora kua showed moderate antifungal activity against Cladosporium cucumerinum.