Dem IPB wird erneut ein beispielhaftes Handeln im Sinne einer chancengleichheitsorientierten Personal- und Organisationspolitik bescheinigt. Das Institut erhält zum 6. Mal in Folge das TOTAL E-QUALITY…
Die Plant Science Student Conference (PSSC) wird seit 20 Jahren im jährlichen Wechsel von Studierenden der beiden Leibniz-Institute IPK und IPB organisiert. Im Interview erläutern Christina Wäsch…
Braga, A. L.; Wessjohann, L. A.; Taube, P. S.; Galetto, F. Z.; de Andrade, F. M.;Straightforward Method for the Synthesis of Selenocysteine and Selenocystine Derivatives from L-Serine Methyl EsterSynthesis20103131-3137(2010)DOI: 10.1055/s-0030-1258188
A set of selenoamino acids has been efficiently synthesized under smooth conditions by a simple, flexible and modular strategy. In this method, O-mesylated l-serine methyl ester is generated in situ and directly substituted with various selenolate anions to afford selenocysteine, selenolanthionine, and selenocystine derivatives in good yields. Also, a tellurocysteine derivative can be obtained by this method.
Publikation
Henze, M.; Kreye, O.; Brauch, S.; Nitsche, C.; Naumann, K.; Wessjohann, L. A.; Westermann, B.;Photoaffinity-Labeled Peptoids and Depsipeptides by Multicomponent ReactionsSynthesis20102997-3003(2010)DOI: 10.1055/s-0030-1258182
Photoaffinity tags can be incorporated easily into peptoids and congeners by the Ugi and Passerini multicomponent reactions. Products related to photo-methionine and photo-leucine can be accomplished by diazirine-containing building blocks. The same protocols can be used to synthesize derivatives with benzophenone photo cross-linkers.