Dem IPB wird erneut ein beispielhaftes Handeln im Sinne einer chancengleichheitsorientierten Personal- und Organisationspolitik bescheinigt. Das Institut erhält zum 6. Mal in Folge das TOTAL E-QUALITY…
Die Plant Science Student Conference (PSSC) wird seit 20 Jahren im jährlichen Wechsel von Studierenden der beiden Leibniz-Institute IPK und IPB organisiert. Im Interview erläutern Christina Wäsch…
Wessjohann, L. A.; Filho, R. A. W. N.; Puentes, A. R.; Morejón, M. C.;Macrocycles from Multicomponent ReactionsMarsault, E. & Peterson, M. L., eds.339-376(2017)ISBN:978-1-11909-259-9DOI: 10.1002/9781119092599.ch14
Macrocyclizations may be performed through two main processes: single‐component reactions and multicomponent reactions (MCRs). This chapter discusses MCRs and details approaches where isonitrile‐based MCRs (IMCRs) were applied to accomplish the macrocyclization of long linear molecules. It also introduces some insights about general aspects, concepts, and classifications of IMCR‐based macrocyclizations. The chapter then focuses on the early development of this method and case studies, where it was applied to the synthesis of rationally designed macrocyclic molecules. It further covers a special topic on the use of multiple IMCR‐based macrocyclizations for synthesizing three‐dimensional structures. In the past, most studies were directed toward understanding the principles of using MCRs in macrocyclizations and to explore the scope of these reactions, especially of the valuable IMCRs. In the future, this will be extended to even more and different MCRs, which in themselves are only at the advent of being explored.