Dem IPB wird erneut ein beispielhaftes Handeln im Sinne einer chancengleichheitsorientierten Personal- und Organisationspolitik bescheinigt. Das Institut erhält zum 6. Mal in Folge das TOTAL E-QUALITY…
Die Plant Science Student Conference (PSSC) wird seit 20 Jahren im jährlichen Wechsel von Studierenden der beiden Leibniz-Institute IPK und IPB organisiert. Im Interview erläutern Christina Wäsch…
Liu, Q.; Neefjes, A. C. M.; Singh, A.; Kobylinska, R.; Mugford, S. T.; Marzo, M.; Canham, J.; Schuster, M.; Hoorn, R. A.; Chen, Y.; Hogenhout, S. A.;Aphid effectors suppress plant immunity via recruiting defense proteins to processing bodiesSci. Adv.11eadv1447(2025)DOI: 10.1126/sciadv.adv1447
Aphids are small insects that have developed specialized mouthparts and effector proteins to establish long-term relationships with plants. The peach-potato aphid
Myzus persicae
is a generalist, feeding on many plant species and capable of transmitting numerous pathogens. This study reveals how host-responsive cathepsin B (CathB) proteins in the oral secretions of
M. persicae
facilitate aphid survival by modulating plant immune responses. Host-responsive CathB proteins localize to plant processing bodies (p-bodies), cytoplasmic ribonucleoprotein granules involved in messenger RNA storage or decay. Upon localization, these CathB proteins recruit key immune regulators EDS1, PAD4, and ADR1 to these bodies, suppressing plant defenses. A plant protein, Acd28.9 (Hsp20 family), counteracts this CathB activity and contributes to plant resistance to aphids. These findings highlight an unexpected role for p-bodies in plant immunity and uncover a plant resistance mechanism to aphid infestation.