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An account of the most commonly used reagents for the introduction of the benzeneselenyl (phenyl seleno) group is given. The review focuses on the various methods of its introduction as auxiliary, modifying or protective entity, and its subsequent removal, thereby often promoting other reactions as cyclizations or double bond formation. Less emphasis is laid on reactions of the phenylselenenylated intermediates with the PhSe‐group left intact utilizing its stabilizing properties on charged intermediates, on reagents with a modified phenyl group, e.g. chiral derivatives, or on reactions not involving intermediate CSe‐bond formation.
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An efficient route for an alternative synthesis of gibberllin A1 from gibberellin A3 is described. Based on iodolactonisation the method provides access to gibberellin A1 labeled by deuterium with both high incorporation of the isotope and high stereoselectity at the positions 1β and 2α. The additional deuterium labeling at C‐17 was introduced via the corresponding 16‐norketone resulting in [1β,2α,17,17‐D4] gibberellin A1.
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