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Better enzymes through Directed Evolution.

Fungal-derived unspecific peroxygenases (UPOs) have emerged over the past two decades as highly efficient biocatalysts for the oxyfunctionalization of…

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Smart against fraud: Saffron substitutes unmasked.

Because of its unique taste, its health-promoting properties and its laborious extraction, saffron is the most expensive spice of all time. As early…

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Structural insights into branch-forming glycosyltransferases.

As if the chemical diversity of plant metabolites were not already vast enough, the repertoire of compounds can be considerably expanded…

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Complex responses to lack of nutrients.

Plants have evolved sophisticated responses to cope with nutrient deficiencies and to free up resources. These responses often vary from one lacking nutrient…

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Beating fungi with bioactives from fungi.

IPB natural product chemists recently produced various derivatives of deoxygenated hygrophorones from the natural fungicide hygrophorone. The final products…

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New anticancer agents by multicomponent reaction.

The bioactive compounds betulinic acid, fusidic acid and cholic acid are currently the subject of intensive research due to their cytotoxic activity.…

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Enigmatic transcription factor.

Glandular trichomes on tomato leaves produce a variety of volatile mono- and sesquiterpenes that play an important role in defense against pathogens and insect pests.…

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Modular enzymes for hemicellulose synthesis.

Fiber, food, fuel - the carbohydrate polymers that encapsulate plants cells have benefited humans for centuries. Arguably the most prominent of these is…

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Mix the sequences! Better enzyme expression by gene shuffling.

News from the UPO front! Nonspecific peroxygenases (UPOs) of fungal origin are popularly used as biocatalysts due to their ability to…

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New anticancer compounds: Tin for the win.

Although cisplatin is currently the drug of choice for fighting various types of cancer, it still causes a number of side effects and damages in particular…

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This page was last modified on 19 Mar 2025 .