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α-Bromo ketones, -esters and -nitriles react with chromium dichloride and ketones in a Barbier-type reaction to yield the kinetic crossed aldol products with one or two new quarternary centers. The reaction does not require special activation of the reagent, proceeds at room temperature and is suitable for microscale preparations. Crotonates react highly regioselective to yield α-products. The influence of solvents is discussed.