Anthelmintic and antimicrobial compounds from Indonesian lichen Parmelia cetrata Ach.
IPB chemists recently published an extensive phytochemical study of Parmelia cetrata, a foliose lichen from Indonesia. They successfully isolated 13 phenol and depside derivatives including previously unreported ones. In assays using the gram-negative bacterium Aliivibrio fischeri and the nematode Caenorhabditis elegans, the researchers evaluated the anti-infective activity of isolated compounds. Two of the tested substances inhibited growth of A. fischeri and one of the substances, in addition, showed significant anthelmintic effects against C. elegans.
Original publication:
Ari Satia Nugraha, Ludmilla Fitri Untari, Annegret Laub, Andrea Porzel, Katrin Franke & Ludger A. Wessjohann (2020) Anthelmintic and antimicrobial activities of three new depsides and ten known depsides and phenols from Indonesian lichen: Parmelia cetrata Ach., Natural Product Research,DOI: 10.1080/14786419.2020.1761361
