The IPB has once again been recognized for its exemplary actions in terms of equal opportunity-oriented personnel and organizational policies and has received the TOTAL E-QUALITY certification for the…
The Plant Science Student Conference (PSSC) has been organised by students from the two Leibniz institutes, IPK and IPB, every year for the last 20 years. In this interview, Christina Wäsch (IPK) and…
Ali, N. A. A.; Wurster, M.; Denkert, A.; Al-Sokari, S. S.; Lindequist, U.; Wessjohann, L.;Cytotoxic and antiphytofungal activity of the essential oils from two artemisia speciesWorld J. Pharm. Res.31350-1354(2014)
Hydrodistilled essential oils from aerial parts of Artemisia abyssinica Sch.Bip. ex A. Rich, and Artemisia arborescens L. growing in Yemen were screened for their cytotoxic and antiphytofungal properties as well as their chemical compositions. Twenty-seven components were identified in the essential oils and the main components of these species were found to be davanone (42.34%), camphor (22.88%), nerolidol (8.96%), and chamazulene (4.46%), from A. abyssinica oil and artemisia ketone (51.05%), camphor (14.09%), α-bisabolol (12.56%) and α-phellandrene (8.69%) from A. arborescens. At concentration of 50 and 25 μg/mL, A. arborescens oil showed a strong cytotoxic activity with growth inhibition of 95%(±1.6) and 74%(±3.8) (IC50 of 16.91 μg/mL) against HT29 tumor cells (Human colonic adenocarcinoma cells), while A. abyssinica oil exhibited at concentration of 100 and 50 μg/mL growth inhibition of 71.0% (±12.5) and 27.3%(±14.4) (IC50 of 75.42 μg/mL) respectively. Bioautographic assay was used to evaluate the antiphytofungal activity of the oils against Cladosporium cucumerinum.