The IPB has once again been recognized for its exemplary actions in terms of equal opportunity-oriented personnel and organizational policies and has received the TOTAL E-QUALITY certification for the…
The Plant Science Student Conference (PSSC) has been organised by students from the two Leibniz institutes, IPK and IPB, every year for the last 20 years. In this interview, Christina Wäsch (IPK) and…
El-Sayed, M. T.; Wessjohann, L.; Porzel, A.; Hilgeroth, A.;Diazatruxenes from the Condensation Reaction of Indoles with NinhydrinJ. Heterocyclic Chem.541077-1083(2017)DOI: 10.1002/jhet.2677
The reaction of indoles with ninhydrin has been reported to provide only 1:1 condensation products (cf. A or 8) that show good antioxidant and anti‐inflammatory activity. In the present work, our synthetic challenge for the synthesis of innovative, highly substituted tetra‐indole indanes of type 1 via a 4:1 condensation reaction in acetic acid gave two unexpected new products, the diazatruxene derivatives 3 and 4. The novel structures have been characterized by their analytical and spectral data including 1D‐ and 2D‐NMR. With 5‐chloroindole, only the known 1:1 reaction.