The IPB has once again been recognized for its exemplary actions in terms of equal opportunity-oriented personnel and organizational policies and has received the TOTAL E-QUALITY certification for the…
The Plant Science Student Conference (PSSC) has been organised by students from the two Leibniz institutes, IPK and IPB, every year for the last 20 years. In this interview, Christina Wäsch (IPK) and…
Braga, A. L.; Appelt, H. R.; Schneider, P. H.; Silveira, C. C.; Wessjohann, L. A.;A new functionalized, chiral disulfide derived from L-cysteine: (R,R)-bis[(3-benzyloxazolan-4-yl)-methane] disulfide as a catalyst in the diethylzinc addition to aldehydesTetrahedron: Asymmetry101733-1738(1999)DOI: 10.1016/S0957-4166(99)00145-7
A new, easily accessible, chiral disulfide 3 was prepared from l-cysteine in a short synthetic sequence (Scheme. 1) and applied successfully as a highly efficient catalyst for the enantioselective addition of diethyl zinc to aromatic and aliphatic aldehydes to afford the product alcohols in up to more than 99% ee. In contrast to the more common amino alcohols used in similar reactions, catalyst 3 does not have a protic hydrogen in the form of a free hydroxy group.