The Plant Science Student Conference (PSSC) has been organised by students from the two Leibniz institutes, IPK and IPB, every year for the last 20 years. In this interview, Christina Wäsch (IPK) and Carolin Apel (IPB)…
Over 600 guests came to the IPB on July 4 for the Long Night of Sciences to learn lots of new things and put their knowledge to the test at our science quiz course. This year, our program was aimed equally at children and…
Our 10th Leibniz Plant Biochemistry Symposium on May 7 and 8 was a great success. This year's theme was new methods and research approaches in natural product chemistry. The excellent presentations on active substances and…
Braga, A. L.; Rubim, R. M.; Schrekker, H. S.; Wessjohann, L. A.; de Bolster, M. W.; Zeni, G.; Sehnem, J. A.;The facile synthesis of chiral oxazoline catalysts for the diethylzinc addition to aldehydesTetrahedron: Asymmetry143291-3295(2003)DOI: 10.1016/j.tetasy.2003.08.029
A range of chiral 4-(1′-hydroxyalkyl)oxazoline catalysts can be obtained in a straightforward two step synthesis, starting from β-hydroxy amino acids like l-serine or l-threonine. Catalyst 4c forms a complex with diethylzinc, effective for the enantioselective addition to aldehydes resulting in high yields and enantiomeric excesses up to >99% even with aliphatic aldehydes. In the latter case the enantiomeric excess showed a marked dependence of the aldehyde's chain length.