@Article{IPB-2570, author = {AntolĂ­n-Llovera, M. and Ried, M. K. and Binder, A. and Parniske, M.}, title = {{Receptor Kinase Signaling Pathways in Plant-Microbe Interactions}}, year = {2012}, pages = {451-473}, journal = {Annu Rev Phytopathol}, doi = {10.1146/annurev-phyto-081211-173002}, url = {https://dx.doi.org/10.1146/annurev-phyto-081211-173002}, volume = {50}, abstract = {Plant receptor-like kinases (RLKs) function in diverse signaling pathways, including the responses to microbial signals in symbiosis and defense. This versatility is achieved with a common overall structure: an extracytoplasmic domain (ectodomain) and an intracellular protein kinase domain involved in downstream signal transduction. Various surfaces of the leucine-rich repeat (LRR) ectodomain superstructure are utilized for interaction with the cognate ligand in both plant and animal receptors. RLKs with lysin-motif (LysM) ectodomains confer recognitional specificity toward N-acetylglucosamine-containing signaling molecules, such as chitin, peptidoglycan (PGN), and rhizobial nodulation factor (NF), that induce immune or symbiotic responses. Signaling downstream of RLKs does not follow a single pattern; instead, the detailed analysis of brassinosteroid (BR) signaling, innate immunity, and symbiosis revealed at least three largely nonoverlapping pathways. In this review, we focus on RLKs involved in plant-microbe interactions and contrast the signaling pathways leading to symbiosis and defense.} }