@Article{IPB-2077,
author = {Braga, A. L. and Rubim, R. M. and Schrekker, H. S. and Wessjohann, L. A. and de Bolster, M. W. and Zeni, G. and Sehnem, J. A.},
title = {{The facile synthesis of chiral oxazoline catalysts for the diethylzinc addition to aldehydes}},
year = {2003},
pages = {3291-3295},
journal = {Tetrahedron: Asymmetry},
doi = {10.1016/j.tetasy.2003.08.029},
volume = {14},
abstract = {A range of chiral 4-(1′-hydroxyalkyl)oxazoline catalysts can be obtained in a straightforward two step synthesis, starting from β-hydroxy amino acids like l-serine or l-threonine. Catalyst 4c forms a complex with diethylzinc, effective for the enantioselective addition to aldehydes resulting in high yields and enantiomeric excesses up to \>99% even with aliphatic aldehydes. In the latter case the enantiomeric excess showed a marked dependence of the aldehyde\'s chain length.}    
}