@Article{IPB-195,
author = {Cheng, Y. and Zhao, H. and Cui, L. and Hussain, H. and Nadolnik, L. and Zhang, Z. and Zhao, Y. and Qin, X. and Li, J. and Park, J. H. and Wang, D.},
title = {{Ultrasonic-assisted extraction of flavonoids from peanut leave and stem using deep eutectic solvents and its molecular mechanism}},
year = {2024},
pages = {137497},
journal = {Food Chem.},
doi = {10.1016/j.foodchem.2023.137497},
url = {https://doi.org/10.1016/j.foodchem.2023.137497},
volume = {434},
abstract = {Natural bioactive compounds extracted from agricultural by-products have received considerable attentions. Twenty-two kinds of deep eutectic solvents (DESs) with ultrasonic were screened to extract flavonoids from peanut leave and stem. ChCl-acetic acid (ChCl-Aa) with 1:2 M ratio resulted in more effective extraction of flavonoids compared to other solvents The best extraction conditions were found to be at a 27% water content in DES/H2O, for 43 min with 31:1 g/mL liquid/solid ratio, giving 2.980 mg/g dw of flavonoids through the response surface method. SEM showed that ChCl-Aa had a certain dissociation impact on the sample matrix, while 1H NMR analysis revealed the formation of hydrogen bonds between daidzein and ChCl-Aa. Changes in the H–bond length and number were observed by the B3LYP/6-31G (d,p) level of theory to confirm the experimental spectra. This study reveals that DESs are efficient for obtaining value-added products and could applied to other natural products.}    
}