@Article{IPB-1304, author = {Gulyas-Fekete, G. and Boluda, C. J. and Westermann, B. and Wessjohann, L. A.}, title = {{Anti-Friedel-Crafts-Type Substitution To Form Biaryl Linkages}}, year = {2013}, pages = {3038-3043}, journal = {Synthesis}, doi = {10.1055/s-0033-1339682}, volume = {45}, abstract = {The ipso-substitution of one (or two) hydroxy groups of phloroglucinol with arene nucleophiles (e.g., o-xylene, tetralin, biphenyl) can be achieved easily under Friedel–Crafts-type conditions with or without the use of organic solvents affording a variety of 3,5-dihydroxybiphenyls (57–89% yields). The new method has significant practical advantages compared to classical biaryl-­coupling routes.} }