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Publikationen - Natur- und Wirkstoffchemie

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Barreto, A. d. F. S.; Vercillo, O. E.; Birkett, M. A.; Caulfield, J. C.; Wessjohann, L. A.; Andrade, C. K. Z.; Fast and efficient microwave-assisted synthesis of functionalized peptoids via Ugi reactions Org. Biomol. Chem. 9, 5024-5027, (2011) DOI: 10.1039/C1OB05471F

A wide range of N-alkylglycines (peptoids) can be efficiently prepared viaUgi reactions using microwave irradiations. The results confirm the versatility and efficiency of the methodology for the preparation of functionalized peptoids. The products can be used in consecutive Ugi reactions to yield cyclic peptoids of potential biological interest.
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