@Article{IPB-1014, author = {Zhang, W. and Ito, H. and Quint, M. and Huang, H. and Noël, L.D. and Gray, W.M.}, title = {{Genetic analysis of CAND1-CUL1 interactions in Arabidopsis supports a role for CAND1-mediated cycling of the SCFTIR1 complex}}, year = {2008}, pages = {8470-8475}, journal = {Proc Natl Acad Sci}, doi = {10.1073/pnas.0804144105}, url = {http://www.pnas.org/content/105/24/8470.full.pdf+html}, volume = {105}, abstract = { SKP1-Cullin1-F-box protein (SCF) ubiquitin-ligases regulate numerous aspects of eukaryotic growth and development. Cullin-Associated and Neddylation-Dissociated (CAND1) modulates SCF function through its interactions with the CUL1 subunit. Although biochemical studies with human CAND1 suggested that CAND1 plays a negative regulatory role by sequestering CUL1 and preventing SCF complex assembly, genetic studies in Arabidopsis have shown that cand1 mutants exhibit reduced SCF activity, demonstrating that CAND1 is required for optimal SCF function in vivo. Together, these genetic and biochemical studies have suggested a model of CAND1-mediated cycles of SCF complex assembly and disassembly. Here, using the SCFTIR1 complex of the Arabidopsis auxin response pathway, we test the SCF cycling model with Arabidopsis mutant derivatives of CAND1 and CUL1 that have opposing effects on the CAND1CUL1 interaction. We find that the disruption of the CAND1CUL1 interaction results in an increased abundance of assembled SCFTIR1 complex. In contrast, stabilization of the CAND1CUL1 interaction diminishes SCFTIR1 complex abundance. The fact that both decreased and increased CAND1CUL1 interactions result in reduced SCFTIR1 activity in vivo strongly supports the hypothesis that CAND1-mediated cycling is required for optimal SCF function.} } @Article{IPB-984, author = {Stenzel, I. and Hause, B. and Proels, R. and Miersch, O. and Oka, M. and Roitsch, T. and Wasternack, C.}, title = {{The AOC promoter of tomato is regulated by developmental and environmental stimuli}}, year = {2008}, pages = {1859-1869}, journal = {Phytochemistry}, doi = {10.1016/j.phytochem.2008.03.007}, volume = {69}, } @Article{IPB-1027, author = {Wasternack, C. and Feussner, I.}, title = {{Multifunctional enzymes in oxylipin metabolism}}, year = {2008}, pages = {2373-2375}, journal = {Chembiochem.}, doi = {10.1002/cbic.200800582}, volume = {9}, } @Article{IPB-1018, author = {Schilling, S. and Wasternack, C. and Demuth, H.U.}, title = {{Glutaminyl cyclases from animals and plants: a case of functionally convergent protein evolution}}, year = {2008}, pages = {983-991}, journal = {Biol. Chem }, doi = {10.1515/BC.2008.111}, volume = {389}, } @Article{IPB-983, author = {Brüx, A. and Liu, T-Y. and Krebs, M. and Stierhof, Y.-D. and Lohmann, J.U. and Miersch, O. and Wasternack, C. and Schumacher, K.}, title = {{Reduced V-ATPase Activity in the trans-Golgi Network Causes Oxylipin-Dependent Hypocotyl Growth Inhibition in Arabidopsis}}, year = {2008}, pages = {1088-1100}, journal = {The Plant Cell}, doi = {10.1105/tpc.108.058362}, volume = {20}, } @Article{IPB-980, author = {Kienow, L. and Schneider, K. and Bartsch, M. and Stuible, H.-P. and Weng, H. and Miersch, O. and Wasternack, C. and Kombrink, E.}, title = {{Jasmonates meet fatty acids: functional analysis of a new acyl-coenzyme A synthetase family from Arabidopsis thaliana}}, year = {2008}, pages = {403-419}, journal = {J. Exp. Bot.}, doi = {10.1093/jxb/erm325}, volume = {59 (2)}, } @Article{IPB-946, author = {Gao, X. and Stumpe, M. and Feussner, I. and Kolomiets, M.}, title = {{A novel plastidial lipoxygenase of maize (Zea mays) ZmLOX6 encodes for a fatty acid hydroperoxide lyase and is uniquely regulated by phytohormones and pathogen infection}}, year = {2008}, pages = {491-503}, journal = {Planta }, doi = {10.1007/s00425-007-0634-8}, volume = {227}, } @Article{IPB-943, author = {Miersch, O. and Neumerkel, J. and Dippe, M. and Stenzel, I. and Wasternack, C.}, title = {{Hydroxylated jasmonates are commonly occurring metabolites of jasmonic acid and contribute to a partial switch-off in jasmonate signaling}}, year = {2008}, pages = {114-127}, journal = {New Phytologist}, doi = {10.1111/j.1469-8137.2007.02252.x}, volume = {177}, }