Research Internship, MSc Thesis in the Designer Glycans Group
Sugars (glycans) are fundamental to all living cells. Plant cell wall polysaccharides represent the most abundant organic polymers on the planet. Heteromannan is regarded as one the most ancient glycans in the plant wall, and serves as a valuable ingredient in foods, cosmetics, and in many other industries. Using synthetic biology, plant heteromannan polysaccharides can be produced orthogonally in the yeast cell wall. Exciting preliminary data is now available for several enzymes whose roles in synthesizing or modifying heteromannan structure and function require further characterization.
We are looking for a highly motivated MSc student who, as part of a research group internship and/or thesis, will expand their knowledge of molecular biology and gain new insight into the biosynthesis of plant polysaccharides. Since the Designer Glycans team is highly international (visit the lab website for more information, www.designerglycans.com), the ability to communicate clearly in English is required. Prior experience with cloning or sterile work would be beneficial.
- Full integration in a young and ambitious team of scientists
- Flexible work hours in a well-equipped molecular research laboratory
- Training in state-of-the-art biochemical analyses of carbohydrates
- Space for creativity, independence, and upward academic mobility
- Synthetic Biology (bioengineering of bacteria, yeast and plants to produce designer polymers)
- Imaging (high-throughput plate screening, fluorescence microscopy of live cells and their walls)
- Carbohydrate analysis (cell wall isolation, ion chromatography, mass spectrometry, and more)