@Article{IPB-375, author = {Mpetga, J. D. S. and Nago, R. D. T. and Tamokou, J.-D.-D. and Fobofou, S. A. T. and Bitchagno, G. T. M. and Wessjohann, L. A. and Tene, M. and Ngouela, A. S.}, title = {{A new ceramide from Cissus aralioides Baker (Vitaceae) and its antimicrobial activity}}, year = {2022}, pages = {e202200678}, journal = {Chem. Biodivers.}, doi = {10.1002/cbdv.202200678}, url = {https://doi.org/10.1002/cbdv.202200678}, volume = {19}, abstract = {Purification through repeated column chromatography over silica gel and Sephadex LH-20 of the ethanol extract of the stems of Cissus aralioides (Baker) Planch. resulted in the isolation of a new ceramide, aralioidamide A (1) along with five known compounds (2-6). Their structures were determined by the extensive analysis of their spectroscopic (1D and 2D NMR) and spectrometric data, and comparison with those reported in the literature. Aralioidamide A (1) displayed weak antibacterial activity (MIC = 256 μg/mL) against Bacillus subtilis, Staphylococcus aureus and Shigella flexneri and was inactive (MIC > 256 μg/mL) against the tested fungi.} }