@Article{IPB-1678,
author = {Baraza, L. D. and Joseph, C. C. and Munissi, J. J. and Nkunya, M. H. and Arnold, N. and Porzel, A. and Wessjohann, L.},
title = {{Antifungal rosane diterpenes and other constituents of Hugonia castaneifolia}},
year = {2008},
pages = {200-205},
journal = {Phytochemistry},
doi = {10.1016/j.phytochem.2007.06.021},
volume = {69},
abstract = {The rosane diterpenoids hugorosenone [3β-hydroxyrosa-1(10),15-dien-2-one], 18-hydroxyhugorosenone and 18-hydroxy-3-deoxyhugorosenone, and 12-hydroxy-13-methylpodocarpa-8,11,13-trien-3-one were isolated as antifungal constituents of H. castaneifolia Engl. root bark, together with the previously reported di-podocarpanoids hugonone A and hugonone B that were weakly active, and 1(10),15-rosadiene-2β,3β-diol (hugorosenol), 4α-methoxyhimachal-10-en-5β-ol (hugonianene B) and 2-hydroxyhenpentacont-2-enal, and the known compounds tetracosyl-(E)-ferrulate and caryophyllene oxide, all of which were inactive. Hugorosenone also exhibited activity against Anopheles gambiae mosquito larvae. Structural determination was achieved based on spectroscopic data.}    
}