By using primary roots of Arabidopsis thaliana and forefront genetic, imaging and analytical approaches, we are currently asking the following questions:
What are the cellular specificities in JA-Ile responses?
The activation of JA-Ile-mediated defense is costly and often accompanied by signiﬁcant growth inhibition. To therefore effectively coordinate growth-defense trade-offs in both space and time, JA-Ile signaling mediated by MYC transcription factors (chiefly MYC2, MYC3 and MYC4) is normally kept repressed by a modular repressor complex of JAZ, NINJA and TPL proteins. The presence of several MYCs and 13 JAZ genes in Arabidopsis, some of which are subjected to alternative splicing, suggests that there is large diversity in small molecule recognition and signaling in different tissues and cell-types. We are currently investigating those cellular specificities in JA-Ile-regulated responses.