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Ichimura, K.; Shinozaki, K.; Tena, G.; Sheen, J.; Henry, Y.; Champion, A.; Kreis, M.; Zhang, S.; Hirt, H.; Wilson, C.; Heberle-Bors, E.; Ellis, B. E.; Morris, P. C.; Innes, R. W.; Ecker, J. R.; Scheel, D.; Klessig, D. F.; Machida, Y.; Mundy, J.; Ohashi, Y.; Walker, J. C.; Mitogen-activated protein kinase cascades in plants: a new nomenclature Trends Plant Sci. 7, 301-308, (2002) DOI: 10.1016/S1360-1385(02)02302-6
Mitogen-activated protein kinase (MAPK) cascades are universal signal transduction modules in eukaryotes, including yeasts, animals and plants. These protein phosphorylation cascades link extracellular stimuli to a wide range of cellular responses. In plants, MAPK cascades are involved in responses to various biotic and abiotic stresses, hormones, cell division and developmental processes. Completion of the Arabidopsis genome-sequencing project has revealed the existence of 20 MAPKs, 10 MAPK kinases and 60 MAPK kinase kinases. Here, we propose a simplified nomenclature for Arabidopsis MAPKs and MAPK kinases that might also serve as a basis for standard annotation of these gene families in all plants.
