Publications

• Nickersen, M. L., Kostiha, B. N., Brandt, W., Fredericks, W., Xu, K.-P., Yu, F.-S., Gold, B., Chodosh, J., Goldberg, M., Lu, D. W., Yamada, M., Tervo, T. M., Grutzmacher, R., Croasdale, C., Hoeltzenbein, M., Sutphin, J., Malkowicz, S. B., Wessjohann, L., UBIAD1 Mutation Alters a Mitochondrial Prenyltransferase to Cause Schnyder Corneal Dystrophy. PloS One. 5, e10760 (2010)

• Biastoff, S., Brandt, W. & Dräger, B. Putrescine N-methyltransferase - The start for alkaloids. Phytochemistry. 70, 1708-1718 (2009)

• Biastoff, S., Reinhardt, N., Reve, V., Brandt, W. & Dräger, B. Evolution of putrescine N-methyltransferase from spermidine synthase demanded alterations in substrate binding. FEBS Lett. 583, 3367-3374 (2009)

• Brandt, W., Bräuer, L., Günnewich, L., Kufka, J., Rausch, F., Schulze, D., Schulze, D., Weber, R., Zakharova, S. & Wessjohann, L. Molecular and structural basis of metabolic diversity mediated by prenyldiphosphate converting enzymes. Phytochemistry. 70, 1758-1775 (2009)

• Wessjohann, L. Zakharova, S., Schulze, D., Kufka, J., Weber, R., Bräuer, L. & Brandt, W. Enzymatic C-C-Coupling Prenylation: Bioinformatics - Modelling - Mechanism - Protein-Redesign - Biocatalytic Application. Chimia. 63, 340-344 (2009)

• Wessjohann, L.A., Schneider, A., Abbas, M., Brandt, W. Selenium in chemistry and biochemistry in comparison to sulfur. Biol. Chem. 388, 997-1006 (2007)

• Horvath, G., Guissez, Y., Wessjohann, L.A., Caubergs, R.J., Horemans, N. Differential distribution of tocopherols and tocotrienols in photosynthetic and non photosynthetic tissues. Phytochemistry. 67, 1185-1195 (2006)

• Horvath, G., Wessjohann, L., Bigirimana, J., Monica, H., Jansen, M., Guisez, Y., Caubergs, R. & Horemans, N. Accumulation of tocopherols and tocotrienols during seed development of grape (Vitis vinifera L. cv. Albert Lavallee). Plant Physiology and Biochemistry. 44, 724-731 (2006)

• Nuhn, P., Wessjohann, L.A. Naturstoffchemie – mikrobielle, pflanzliche und tierische Naturstoffe. S. Hirzel Verlag, Stuttgart (Germany). 4th editio, 656 (2006) ISBN:3-7776-1363-0

• Wessjohann, L.A., Fulhorst, M., Zakharova, S. Synthesis of Mechanistic Probes and Inhibitors for Prenylating Enzymes. Polish J. Chem. 80, 673-678 (2006)

• Basso, A., Ebert, C., Gardossi, L., Linda, P., Phuong, T. T., Zhu, M., Wessjohann, L. A. Penicillin G amidase-catalysed hydrolysis of phenylacetic hydrazides on a solid phase: A new route to enzyme-cleavable linkers. Adv. Synth. & Catal. 347, 963-966 (2005)

• Brandt, W., Wessjohann, L. A. The functional role of selenocysteine (Sec) in the catalysis mechanism of large thioredoxin reductases: Proposition of a swapping catalytic triad including a sec-his-glu state. ChemBioChem. 6, 386-394 (2005)

• Ödman, P., Wessjohann, L. A., Bornscheuer, U. T. Chemoenzymatic dynamic kinetic resolution of acyloins. J. Org. Chem. 70, 9551-9555 (2005)

• Brandt, W. , Wessjohann, L.A. Structure of the mitochondrial thiorexoin reductase in complex with thioredoxin. Brookhaven Protein Data Bank. entry 1w1e, (2004)

• Brandt, W., Wessjohann, L.A. A 3D-model of the fragment L271 to A375 of the enzyme GcpE of Streptomyces coelicolor. Brookhaven Protein Data Bank. entry 1ox2, (2004)

• Brandt, W., Wessjohann, L.A. Structure of the cytosolic thioredoxin reductase (txn1) in complex with thioredoxin. Brookhaven Protein Data Bank. entry 1w1c, (2004)

• Brandt, W., Dessoy, M.A., Fulhorst, M., Gao, W., Zenk, M.H., Wessjohann, L.A. Structural Basis for the Reductive Ring Opening of the Cyclodiphosphate MEcPP, a Crucial Transformation in the New DXP/MEP-Pathway to Isoprenoids. ChemBioChem. 5, 311-323 (2004)

• Galm, U., Dessoy, M.A., Schmidt, J., Shu-Ming Li, Wessjohann, L.A., Heide L. In vitro and in vivo production of new aminocoumarins by a combined biochemical, genetic and synthetic approach. Chem. Biol. 11, 173-183 (2004)

• Horvath, G., Wessjohann, L.A., Guissez, Y., Biebaut, E., Caubergs, R.J. , Horemans, N. Seeds of grapes of Vitis vinfera var. Alphonse Lavallée (Royal) - a possible model tissue for studying tocotrienol biosynthesis. Acta Horticulturae. 652, 415-424 (2004)

• Scheid, G., Ruijter, E., Konarzycka-Bessler, M., Bornscheuer, U.T., Wessjohann, L.A. Synthesis and resolution of a key building block for epothilones – a comparison of asymmetric synthesis, chemical, and enzymatic resolution. Tetrahedron: Asymmetry. 15, 2861-2869 (2004)

• Scheid. G., Kuit, W., Ruijter, E., Orru, R.V.A., Henke, E., Bornscheuer, U., Wessjohann, L.A. A New Route to Protected Acyloins and their Enzymatic Resolution with Lipases. Eur. J. Org. Chem. 1063-1074 (2004)

• Zakharova, S., Fulhorst, M., Luczak, L., Wessjohann, L.A. Synthesis, Inhibitory and Activation Properties of Prenyldiphosphate Mimics for Aromatic Prenylations with ubiA-Prenyl Transferase. Arkivoc. 79-96 (2004)

• Zhu, M., Ruijter, E., Wessjohann, L.A. A New Scavenger Resin for the Reversible Linking and Monoprotection of Functionalized Aromatic Aldehydes. Org. Lett. 6, 3921-3924 (2004)

• Wessjohann, L.A., Brandt, W., Tiemann, T. Biosynthesis and Metabolism of Cyclopropane-Rings in Natural Compounds. Chem. Rev. 103, 1625-1647 (2003)

• Gao, W., Loeser, R., Raschke, M., Dessoy, M.A., Fulhorst, M., Alpermann, H., Wessjohann, L.A., Zenk, M.H. (E)-4-Hydroxy-3-methylbut-2-enyl Diphosphate: An Intermediate in the Formation of Terpenoids in Plant Chromoplasts. Angew. Chem., Angew. Chem. Int. Ed. 114, 2716-2719 (2002)

• Wessjohann, L.A., Sontag, B., Dessoy, M.A. Enzymatic C-C-Coupling: The Development of Aromatic Prenylation for Organic Synthesis. (H.-G. Schmalz, ed., eds.) Bioorganic Chemistry – Highlights and New Aspects, Wiley-VCH, Weinheim, Organic Chemistry Highlights IV, Wiley-VCH, Weinheim. 79-88 (1999)

• Wessjohann, L.A., Sontag, B. Development of an Enzymatic C-C-Coupling: The Prenylation of Aromatic Compounds - Entwicklung einer Enzymatischen C-C-Verknüpfung: Die Prenylierung von Aromaten. GIT Fachz. f. Lab. 42, 229-230 (1998)

• Wessjohann, L.A., Sonntag, B. Prenylation of Benzoic Acid Derivatives Catalyzed by a Transferase from Escherichia coli Overproduction: Method Development and Substrate Specificity. Angew. Chem. Int. Ed. Engl. 35, 1697-1699 (1996)

• Wessjohann, L.A., Sontag, B. Prenylierung von Benzoesäurederivaten katalysiert durch eine Transferase aus Escherichia coli-Überproduzenten: I. Verfahrensentwicklung und Substratspezifität. Angew. Chem. 108, 1821-1823 (1996)