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SPP 1152 "Evolution of Metabolic Diversity"
6thFinal Colloquium
Stiftung Bildungszentrum, Kardinal-Döpfner-Haus


Friday, April 3, 2009

14.00 Opening remarks

Part I
Chair:


LUTZ HEIDE

14:10 TOBIAS KÖLLNER (Halle)
Evolution of terpene synthase mechanisms responsible for the production of plant defense signals


14:40 ERICH GLAWISCHNIG (München)
Evolution of camalexin and structurally related indolic compounds


15:10 ALFONS GIERL (München)
Evolution of benzoxazinone biosynthesis


15:40 MILTON T. STUBBS (Halle)
Evolution of adenylation domain specificity: A structural perspective


16:10 JÖRG ZIEGLER (Calgary, Kanada)
Evolution of benzylisoquinoline metabolism in Papaver somniferum


16:40 COFFEE BREAK

Part II
CHAIR:

JÖRG DEGENHARDT

17:10 BIRGIT DRÄGER (Halle)
Putrescine N-methyltransferase - The start for alkaloids


17:40 CARSTEN MILKOWSKI (Jena)
Structure-function relationships of SCPL acyltransferases of plant phenylpropanoid metabolism


  GUEST LECTURE

18:10 SAM MUGFORD (Norwich, United Kingdom)
A serine carboxypeptidase-like acyltransferase from oat required for the synthesis of anti-microbial defence compounds


19:00 Dinner

Saturday, April 4, 2009

Part II  
  GUEST LECTURE

08:30 KAZUKI SAITO(Yokohama, Japan)
Phytochemical genomics - A basis for chemical diversity of plants

Chair: JÖRG DEGENHARDT

09:30 JÜRGEN KROYMANN (Paris, Frankreich)
Loss of metabolic diversity? - Glucosinolates in the Cleomaceae

10:00 MARKUS PIOTROWSKI (Bochum)
Loss of metabolic diversity? - Glucosinolates in the Cleomaceae


10:30 COFFEE BREAK

Part III  
Chair: ERICH GLAWISCHNIG

11:00 DIETRICH OBER (Kiel)
Evolution of plant defense exemplified with the pyrrolizidine alkaloids

11:30 MAIKE PETERSEN (Marburg)
Evolution of rosmarinic acid biosynthesis

12:00 UTE WITTSTOCK (Braunschweig)
Biochemistry and evolution of glucosinolate hydrolysis in plants - The role of specifier proteins

12:30 MARCO MATUSCHEK (Marburg)
Evolution of aromatic prenyltransferases in the biosynthesis of indole derivatives


13:00 LUNCH

14:00 LUTZ HEIDE (Tübingen)
Prenyl transfer to aromatic substrates in the biosynthesis of aminocoumarins, meroterpenoids and phenazines: The ABBA prenyltransferase family

14:30 WOLFGANG BRANDT (Halle)
Molecular and structural reasons of metabolic diversity mediated by prenyl converting enzymes

15:00 ANDREAS IRMER (Würzburg)
Convergence in biosynthesis of acetate derived natural products from plants, fungi and bacteria


15:30 COFFEE BREAK

16:00 ELKE DITTMANN (Berlin)
Cyanothiazol - Evolutionary and functional insights into polyketides produced by cyanobacteria

16:30 WOLFGANG WOHLLEBEN (Tübingen)
Phosphinothricin-tripeptide biosynthesis: An original version of bacterial secondary metabolism?

17:00 CHRISTINE SCHIMEK (Jena)
Carotene degradation products in speciation and communication of zygomycete fungi


18:00 DINNER

19:00 VISITING THE MARIENDOM FREISING

Sunday, April 5, 2009

Part IV  
  GUEST LECTURE

08:30 KAZUFUMI YAZAKI (Kyoto, Japan)
Prenylation of polyphenols, a key diversification of aromatic secondary metabolites

Chair: ELKE DITTMANN

09:30 MARCEL THÖN (Jena)
Evolution and function of cis-/trans elements of fungal secondary metabolism with emphasis on the penicillin biosynthesisi

10:00 CHRISTIAN HERTWECK (Jena)
Evolution of metabolic diversity in polyketide-derived pyrones: Using the non-colinear aureothin assembly line as a model system


10:30 COFFEE BREAK

11:00 ANDREAS BECHTHOLD (Freiburg)
Function and specificity of glycosyltransferases

11:30 BETTINA TUDZYNSKI (Münster)
Evolution of the gibberellin (GA) biosynthesis pathway in plants, fungi, and bacteria

12:00 PAUL TUDZYNSKI (Münster)
The ergot alkaloid gene cluster: Functional analyses and evolutionary aspects

12:30 JÖRN PIEL (Bonn)
Phylogeny-based strategies to study polyketide synthases of sponge-bacterial associations


13:00 LUNCH

14:00 ROLF MÜLLER (Saarbrücken)
Biosynthesis of quinoline alkaloid aurachins from Stigmatella aurantiaca

14:30 LUDGER BEERHUES (Braunschweig)
Biosynthesis of biphenyls and benzophenones - Evolution of benzoic acid-specific type III polyketide synthases in plants

15:00 MICHAEL MÜLLER (Freiburg)
Stereoselective oxidative phenol coupling in filamentous fungi

15.30 Closing remarks

15.45 Departure